Bowel cancer: New research shows possible link with abnormal glucose metabolism
Scientists have discovered a new link between diabetes and bowel cancer. People with diabetes could be up to three times more likely to get bowel cancer, according to a report published by the Medical Research Council and Cancer Research UK.
A group of 10,000 men and women aged between 45 and 79 had blood samples tested for sugar levels and then six years later their health was checked again. It was found that people with abnormal glucose metabolism, which can lead to diabetes, were more likely to develop bowel cancer.
The findings mean that doctors will now be looking at ways to help prevent more people getting high blood sugar levels in the first place.
"The study shows that high sugar levels, even when they are below those of diagnosed diabetes, could be linked to increased risk of bowel cancer. More research is needed but if the results of our study are confirmed they would be important in developing prevention strategies," said Professor Key-Tee Khaw, who led the study.
Out of all the participants who took part in the study, 67 were found to have developed bowel cancer six years later. Diabetics were three times more likely to develop the condition and the trend was found to be stronger among men.
The reason for the link between diabetes and bowel cancer could, according to researchers, be that both conditions share common predisposing factors. Professor Khaw said a high fibre diet and regular exercise could help prevent both diseases.
"Understanding these metabolic changes and the lifestyle factors responsible may help us to prevent and treat cancer," she said.
Hormonal changes associated with diabetes could also add to the risk of developing a tumour, according to the report.
Professor Robert Souhami, director of clinical and external affairs, said the research could herald some important developments.
"Colerectal cancer is one of the most common cancers and is the second most common cause of cancer death. This puts it at the top of the research agenda and any information that helps formulate prevention strategies is welcome," he said.
